MICROANATOMY

Detailed explanation-1: -The adrenal cortex produces several hormones. The most important are aldosterone (a mineralocorticoid), cortisol (a glucocorticoid), and androgens and estrogen (sex hormones). Aldosterone helps the kidneys control the amount of salt in the blood and tissues of the body.

Detailed explanation-2: -The adrenal glands make the hormones cortisol, aldosterone, adrenaline, and noradrenaline. They also make hormones that your body uses to make sex hormones (estrogen and testosterone).

Detailed explanation-3: -The adrenal cortex-the outer part of the gland-produces hormones that are vital to life, such as cortisol (which helps regulate metabolism and helps your body respond to stress) and aldosterone (which helps control blood pressure).

Detailed explanation-4: -Aldosterone is controlled by the renin-angiotensin system, while the rest of the adrenal glands’ hormone production is controlled by adrenocorticotropic hormone (ACTH). Therefore, in cases of Addison’s disease caused by pituitary dysfunction, adrenal insufficiency will exist, but with appropriate aldosterone levels.

Detailed explanation-5: -Aldosterone, the primary mineralocorticoid, is synthesized in the outer zone of the adrenal cortex called the zona glomerulosa (ZG).