MICROANATOMY

Detailed explanation-1: -Acromegaly and gigantism are due to the oversecretion of growth hormone. The most common cause is a GH-secreting pituitary adenoma . Rarely, ectopic GH secretion or excess secretion of GHRH may be the cause.

Detailed explanation-2: -Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism.

Detailed explanation-3: -Hypersecretion of hGH in a adulthood causes disproportionate gigantism.

Detailed explanation-4: -Acromegaly is a disorder that occurs when your body makes too much growth hormone (GH). Produced mainly in the pituitary gland, GH controls the physical growth of the body. In adults, too much of this hormone causes bones, cartilage, body organs, and other tissues to increase in size.

Detailed explanation-5: -High levels of human growth hormone over a long period can produce irreversible acromegaly, but even smaller doses can lead to complications such as heart disease and diabetes.