MICROANATOMY

ENDOCRINE ORGANS AND RESPIRATORY SYSTEM

ENDOCRINE ORGANS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A patient of diabetes insipidus faces the problem of producing a large amount of urine and often feeling thirsty. Why?
A
The pituitary gland fails to secrete ADH
B
The pituitary gland secretes excessive ADH
C
Excessive amount of water is reabsorbed at the renal tubule and the collecting duct
D
Too little or no water is reabsorbed at the renal tubule and the collecting duct
Explanation: 

Detailed explanation-1: -In a healthy person, AVP acts as a signal to the nephrons to reabsorb water into the body. In nephrogenic diabetes insipidus, the nephrons in the kidneys are not able to respond to this signal, leading to excessive water loss in large amounts of urine.

Detailed explanation-2: -Diabetes insipidus is a rare disorder that causes the body to make too much urine. While most people make 1 to 3 quarts of urine a day, people with diabetes insipidus can make up to 20 quarts of urine a day. People with this disorder need to urinate frequently, called polyuria.

Detailed explanation-3: -In diabetes insipidus, the lack of production of AVP means the kidneys cannot make enough concentrated urine and too much water is passed from the body. In rare cases, the kidneys do not respond to AVP. This causes a specific form of diabetes insipidus called nephrogenic diabetes insipidus.

Detailed explanation-4: -Overview. Diabetes insipidus (die-uh-BEE-teze in-SIP-uh-dus) is an uncommon problem that causes the fluids in the body to become out of balance. That prompts the body to make large amounts of urine. It also causes a feeling of being very thirsty even after having something to drink.

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