MICROANATOMY

Detailed explanation-1: -Growth hormone is produced by our brain’s pituitary gland and governs our height, bone length and muscle growth. Some people abuse synthetic growth hormone in the mistaken belief it will help them increase muscle size and strength.

Detailed explanation-2: -GH directly and through IGF-I stimulates osteoblast proliferation and activity, promoting bone formation. It also stimulates osteoclast differentiation and activity, promoting bone resorption. The result is an increase in the overall rate of bone remodeling, with a net effect of bone accumulation.

Detailed explanation-3: -The growth hormone/IGF-1 system stimulates both the bone-resorbing and bone-forming cells, but the dominant effect is on bone formation, thus resulting in an increase in bone mass. Thyroid hormones increase the energy production of all body cells, including bone cells.

Detailed explanation-4: -The growth hormone enhances growth in adolescents and children. It also contributes to the regulation of body fluids, fat metabolism, sugar and also the functions of the heart. The growth hormone reduces body fat by increasing bone density and muscle mass.