MICROANATOMY

Detailed explanation-1: -In gigantism, the excessive amount of growth hormone (GH) accelerates the growth of muscle, bones and connective tissue. This leads to an abnormally increased height as well as several soft tissue changes. When left untreated or unmanaged, some people with gigantism have grown over 8 feet tall.

Detailed explanation-2: -Gigantism is very similar to acromegaly. Acromegaly is also caused by excess growth hormone secretion however, this happens during adulthood rather than childhood. This means that height is normal as the growth plates have fused before the excess growth hormone secretion occurs.

Detailed explanation-3: -Children with gigantism can lead a normal life. If they are treated successfully, they will not get most of the serious complications. However, children with gigantism can still have symptoms such as muscle weakness. Others may have psychological problems.