MICROANATOMY

Detailed explanation-1: -In a negative feedback mechanism, high levels of a hormone turn off further release of that hormone. This usually occurs in a stepwise pattern: the high concentration of the hormone signals back through the system to turn off production of the hormone or hormones that stimulated its release.

Detailed explanation-2: -Through a process called homeostasis, the endocrine system helps maintain a constant internal environment in the body.

Detailed explanation-3: -Homeostasis is the tendency to resist change in order to maintain a stable, relatively constant internal environment. Homeostasis typically involves negative feedback loops that counteract changes of various properties from their target values, known as set points.

Detailed explanation-4: -Negative feedback keeps the concentration of a hormone within a relatively narrow range and maintains homeostasis. Very few endocrine hormones are regulated by positive feedback loops. Positive feedback causes the concentration of a hormone to become increasingly higher.