MICROANATOMY

Detailed explanation-1: -Estradiol is one of three estrogen hormones naturally produced in the body. The effects of estradiol are clearly seen in women experiencing menopause. During this process, women naturally have lower levels of estradiol as the ovaries no longer produce it, causing the menstrual cycles to stop.

Detailed explanation-2: -During menopause, a woman’s ovaries stop releasing eggs. The body produces less of the female hormones estrogen and progesterone. Lower levels of these hormones cause menopause symptoms.

Detailed explanation-3: -With menopause, your estrogen levels drop and you no longer ovulate. The decrease in estrogen may lead to symptoms like vaginal dryness, mood changes, night sweats and hot flashes. The primary estrogen in your body changes from estradiol (E2) to estrone (E1) during menopause.

Detailed explanation-4: -Before menopause, most estrogens are produced in the ovaries. After menopause, the ovaries no longer produce much estrogen and estrogens mainly come from fat tissue. After menopause, higher amounts of estrogen in the blood are linked to an increased risk of breast cancer in women [21].