MICROANATOMY

Detailed explanation-1: -Left untreated, Cushing syndrome can result in exaggerated facial roundness, weight gain around the midsection and upper back, thinning of the arms and legs, easy bruising, and stretch marks. Cushing syndrome occurs when your body has too much of the hormone cortisol over time.

Detailed explanation-2: -Hypersecretion of the glucocorticoid hormone cortisol leads to a disorder named Cushing’s syndrome. The most common cause of Cushing’s syndrome is a pituitary tumor, which causes excessive production of ACTH.

Detailed explanation-3: -Cushing’s syndrome is a disorder caused by the body’s exposure to an excess of the hormone cortisol. Cortisol affects all tissues and organs in the body. These effects together are known as Cushing’s syndrome.

Detailed explanation-4: -High levels of the hormone cortisol can lead to increased fat synthesis. With Cushing syndrome, the fat produced often deposits in the neck, known as lipodystrophy. This produces the characteristic buffalo hump.

Detailed explanation-5: -People with Cushing’s syndrome may see their face get round ("moon face"), they gain weight in unusual ways, bruise easily or feel weak, tired and sad. Women and men may also notice fertility and other problems. CS is most often found in adults between the ages of 20 and 50.