MICROANATOMY

Detailed explanation-1: -Hyposecretion of the glucocorticoid hormone cortisol leads to a disorder named Addison’s disease. There may also be hyposecretion of mineralocorticoids with this disorder.

Detailed explanation-2: -Addison’s disease, also called adrenal insufficiency, is an uncommon illness that occurs when the body doesn’t make enough of certain hormones. In Addison’s disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone.

Detailed explanation-3: -Hyposecretion of the adrenal glands can be caused due to the destruction of the cells of the adrenal glands by the body’s own immune system. Addison’s disease is characterized by fatigue, muscle weakness, weight loss, darkening of the skin, and low blood pressure.

Detailed explanation-4: -Hypersecretion from adrenal cortex causes Cushing’s syndrome. Symptoms of this disease include obesity, hyperglycemia, osteoporosis and water retention.