MICROANATOMY

Detailed explanation-1: -They are not fat soluble, so they cannot diffuse across the plasma membrane of target cells. Instead, a non-steroid hormone binds to a receptor on th e cell membr ane (see Figure below). The binding of the hormone triggers an enzyme inside the cell membrane.

Detailed explanation-2: -A nonsteroid hormone binds to receptors on the cell membrane. 2. The binding of the hormone activates enzymes on the inner surface of the cell membrane.

Detailed explanation-3: -Lipid-insoluble hormones bind to receptors on the outer surface of the plasma membrane, via plasma membrane hormone receptors. Unlike steroid hormones, lipid-insoluble hormones do not directly affect the target cell because they cannot enter the cell and act directly on DNA.

Detailed explanation-4: -Steroid hormones are lipid soluble and can pass through target cell membranes, whereas most nonsteroid hormones are not and must bind to receptors on cell surface membranes.

Detailed explanation-5: -Cell membrane – The cell membrane contains receptors for protein hormones and adrenal medullary hormones (catecholamines) Cytoplasm – Steroid hormone receptors are found in the cytoplasm of target cells.