MICROANATOMY

Detailed explanation-1: -Synaptic vesicles (SVs) are small, electron-lucent vesicles that are clustered at presynaptic terminals. They store neurotransmitters and release them by calcium-triggered exocytosis. SVs are made locally at the terminals and are regenerated after exocytosis.

Detailed explanation-2: -In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for propagating nerve impulses between neurons and are constantly recreated by the cell.

Detailed explanation-3: -At rest, neurotransmitter-containing vesicles are stored at the terminal of the neuron in one of two places. A small number of vesicles are positioned along the pre-synaptic membrane in places called “active zones.” This is where neurotransmitter release occurs.

Detailed explanation-4: -Synaptic vesicles play the central role in synaptic transmission. They are regarded as key organelles involved in synaptic functions such as uptake, storage and stimulus-dependent release of neurotransmitter.