MICROANATOMY

Detailed explanation-1: -Prolactin is synthesized by lactotrophs in the anterior pituitary gland. The number of lactotrophs will increase during pregnancy in response to the physiological need to develop breast tissues and to prepare for milk production.

Detailed explanation-2: -Prolactin (PRL) released from lactotrophs of the anterior pituitary gland in response to the suckling by the offspring is the major hormonal signal responsible for stimulation of milk synthesis in the mammary glands.

Detailed explanation-3: -Dopamine (a brain chemical) and estrogen (a hormone) control prolactin production and release from your pituitary gland. Your central nervous system, immune system, uterus and mammary glands are also capable of producing prolactin.

Detailed explanation-4: -Prolactin is a protein hormone secreted by the acidophilic lactotroph cells of the anterior pituitary gland. Chemically, prolactin is similar to a growth hormone composing of 199 amino acids, and forms after a 28-amino acid signal peptide are proteolytically cleaved from the prolactin prohormone (pre-prolactin).

Detailed explanation-5: -Prolactin is the hormone that is responsible for lactation in women. It has no known function in healthy men. Prolactinoms are the most common type of pituitary tumor.