ENDOCRINE ORGANS AND RESPIRATORY SYSTEM
ENDOCRINE ORGANS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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epinephrine binding to it
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an activated G protein
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cAMP
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a protein kinase
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Detailed explanation-1: -Adenylyl cyclase can be activated directly by forskolin, a plant diterpene which has been useful in studies of enzyme regulation and purification.
Detailed explanation-2: -GTP-bound Gs alpha then binds to and stimulates adenylyl cyclase. Adenylyl cyclase is a membrane-bound enzyme that catalyzes the conversion of ATP to cAMP.
Detailed explanation-3: -Adenylyl cyclases are often activated or inhibited by G proteins, which are coupled to membrane receptors and thus can respond to hormonal or other stimuli.
Detailed explanation-4: -Adenylate cyclase integrates positive and negative signals that act through G protein-coupled cell-surface receptors with other extracellular stimuli to finely regulate levels of cAMP within the cell.