MICROANATOMY

Detailed explanation-1: -CRH stimulates the anterior pituitary to release ACTH. ACTH acts on the adrenal cortex to release cortisol and androgens. The increase in cortisol provides a negative feedback system to decrease the amount of CRH released from the hypothalamus.

Detailed explanation-2: -ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol.

Detailed explanation-3: -CRH stimulates your anterior pituitary lobe to release ACTH. ACTH then triggers your adrenal glands, specifically your adrenal cortex, to release cortisol and androgens. The resulting increase in cortisol then signals your hypothalamus to decrease CRH levels, thus completing the feedback loop.

Detailed explanation-4: -What hormones are secreted by the anterior pituitary? Your anterior pituitary produces and releases (secretes) six main hormones: Adrenocorticotropic hormone (ACTH, or corticotropin): This hormone stimulates your adrenal glands (the glands on top of your kidneys) to produce cortisol and other hormones.

Detailed explanation-5: -ACTH primarily functions to regulate cortisol and androgen production. The ACTH released from the anterior pituitary acts on its target organ, the Adrenal gland, and stimulates the production of Glucocorticoids from the Zona Fasiculata and androgens from the Zona Reticularis.