MICROANATOMY

Detailed explanation-1: -the mineralocorticoid receptor (MR) is essential for blood pressure regulation and electrolyte homeostasis. Physiologically, the MR mediates effects of the hormone aldosterone on electrolyte balance, promoting Na+ retention and K+ excretion.

Detailed explanation-2: -Electrolyte and Water Balance The major effect of mineralocorticoids is the regulation of electrolyte excretion in the kidney.

Detailed explanation-3: -Mineralocorticoids, such as aldosterone, promote sodium reabsorption in transporting epithelia of the kidneys, salivary glands, and large intestine. Sodium reabsorption is followed by passive reabsorption of water.

Detailed explanation-4: -Aldosterone is the endogenous mineralocorticoid and is of fundamental importance in the maintenance of water and electrolyte balance, producing sodium and water retention and potassium excretion.

Detailed explanation-5: -Mineralocorticoids are a class of steroid hormones that regulate salt and water balances. Aldosterone is the primary mineralocorticoid. Mineralocorticoids promote sodium and potassium transport, usually followed by changes in water balance. This function is essential to life.