MICROANATOMY

Detailed explanation-1: -These G proteins are attached to the cytoplasmic face of the plasma membrane, where they serve as relay molecules, functionally coupling the receptors to enzymes or ion channels in this membrane.

Detailed explanation-2: -The classical view of heterotrimeric G protein signaling places G proteins at the cytoplasmic surface of the cell’s plasma membrane where they are activated by an appropriate G protein-coupled receptor.

Detailed explanation-3: -G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.

Detailed explanation-4: -G protein-coupled receptor (GPCR), also called seven-transmembrane receptor or heptahelical receptor, protein located in the cell membrane that binds extracellular substances and transmits signals from these substances to an intracellular molecule called a G protein (guanine nucleotide-binding protein).

Detailed explanation-5: -G protein-coupled receptors (GPCRs) are integral membrane proteins that reside in the plasma membrane of eukaryotic cells. They are central to transmitting signals from the extracellular milieu to the inside of the cell.