MICROANATOMY

Detailed explanation-1: -The thyroid gland secretes the thyroxine hormone in the bloodstream. Thyroxine hormone acts as a regulator of the metabolic rate of the body. Its primary function is to stimulate the metabolism of carbohydrates, proteins, and fats in the cells to produce energy.

Detailed explanation-2: -Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. It plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones.

Detailed explanation-3: -Local activation of thyroxine (T4), to the active form, triiodothyronine (T3), by 5′-deiodinase type 2 (D2) is a key mechanism of TH regulation of metabolism. D2 is expressed in the hypothalamus, white fat, brown adipose tissue (BAT), and skeletal muscle and is required for adaptive thermogenesis.

Detailed explanation-4: -The thyroid keeps your metabolism under control through the action of thyroid hormone, which it makes by extracting iodine from the blood and incorporating it into thyroid hormones. Thyroid cells are unique in that they are highly specialized to absorb and use iodine.

Detailed explanation-5: -The thyroid gland produces thyroxine (referred to as T4), which is a relatively inactive prohormone, and the highly active hormone called triiodothyronine (referred to as T3). Collectively, thyroxine and triiodothyronine are referred to as the thyroid hormones.