MICROANATOMY

Detailed explanation-1: -Human growth hormone (HGH), also known as somatotropin, is a protein of 191 amino acid single chain polypeptides secreted by the acidophilic somatotropic cells of the anterior pituitary gland .

Detailed explanation-2: -Growth hormone (GH) – this hormone stimulates growth in children and participates in maintaining various body tissues/organs in adults, including bones, liver, and fat and muscle tissues. In adults, the overproduction of GH causes acromegaly, which is characterized by increased bone size.

Detailed explanation-3: -Pituitary synthesis and secretion of GH is stimulated by episodic hypothalamic hormones. Growth hormone releasing hormone (GHRH) stimulates while somatostatin (SST) inhibits GH production and release. GH stimulates IGF-I production which in turn inhibits GH secretion at both hypothalamic and pituitary levels.