MICROANATOMY

Detailed explanation-1: -Complications of hyperparathyroidism are mainly related to the long-term effect of too little calcium in your bones and too much calcium in your bloodstream. Common complications include: Osteoporosis. The loss of calcium from bones often results in weak, brittle bones that break easily (osteoporosis).

Detailed explanation-2: -Hyperparathyroidism and bone health. Hyperparathyroidism can increase your risk of osteoporosis and broken bones. Hyperparathyroidism is a condition where the parathyroid glands release too much parathyroid hormone. This can lead to high levels of calcium in the blood.

Detailed explanation-3: -Bone involvement is typically characterized as salt-and-pepper appearance in the skull, bone erosions and bone resorption of the phalanges, brown tumors and cysts. In the radiography, diffuse demineralization is observed, along with pathological fractures, particularly in the long bones of the extremities.

Detailed explanation-4: -Introduction: Primary hyperparathyroidism (PHPT) is associated with an increase in the risk of fracture. In FRAX, the increase in risk is assumed to be mediated by low bone mineral density (BMD). However, the risk of death is also increased and its effect on fracture probability is not known.