MICROANATOMY

Detailed explanation-1: -The olfactory nerve is a solely sensory nerve and conveys the sense of smell. Its receptors are located in the olfactory mucosa under the roof of the nasal cavity. The olfactory fibers cross the skull base through the olfactory foramina of the cribriform plate and enter the olfactory bulb in the olfactory groove.

Detailed explanation-2: -Your ability to smell comes from specialized sensory cells, called olfactory sensory neurons, which are found in a small patch of tissue high inside the nose. These cells connect directly to the brain. Each olfactory neuron has one odor receptor.

Detailed explanation-3: -Olfactory receptors are able to detect air-borne odour molecules that enter the nasal cavity and bind to olfactory receptors. The activation of olfactory receptors results in olfactory receptor neurons sending an impulse to the brain’s olfactory system.

Detailed explanation-4: -Accordingly, they are categorized into several receptor families, including odorant receptors (ORs), vomeronasal receptors (V1Rs and V2Rs), trace amine-associated receptors (TAARs), formyl peptide receptors (FPRs), and the membrane guanylyl cyclase GC-D.

Detailed explanation-5: -Olfactory mucosa is found in the nasal mucosa-in a small region of the roof of the nasal cavities. It is here where there are receptors for sense of smell. The cells coloured yellow in the diagram are the olfactory receptor cells. These are bipolar neurones.