ENDOCRINE ORGANS AND RESPIRATORY SYSTEM
THYROID
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Peripheral monodeiodination of T4 produces how much additional T3?
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25 mg
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25 mcg
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15 mg
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5 mcg
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Explanation:
Detailed explanation-1: -It is suggested to start T4 + T3 combination therapy in a L-T4:L-T3 dose ratio between 13:1 and 20:1 by weight [1]. The serum FT3/FT4 ratio (pmol/l to pmol/l) in hypothyroid patients replaced with L-T4 is 0.24 (IQR 0.20–0.28), lower than the value of 0.32 (IQR 0.27–0.37) in euthyroid controls [16].
Detailed explanation-2: -The thyroid produces approximately 90% inactive thyroid hormone, or thyroxine (T4), and 10% active thyroid hormone, or triiodothyronine (T3).
There is 1 question to complete.