ENDOCRINE ORGANS AND RESPIRATORY SYSTEM
THYROID
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Thyroglobulin
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Albumin
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Thyroxine binding globulin
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Thyrpoeroxidase
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Detailed explanation-1: -The major constituent of colloid is the large glycoprotein thyroglobulin. The endoplasmic reticulum and Golgi apparatus synthesize and secrete the thyroglobulin into the follicles. Thyroglobulin contains the thyroid hormones, T3 and T4, within its molecule.
Detailed explanation-2: -Thyroglobulin is the most abundant protein in the thyroid gland, and the protein backbone for synthesis of T3 and T4 hormones. The most stable form of Tg is a 660 kDa glycoprotein built of two chains (12S forms), 330 kDa each [68].
Detailed explanation-3: -The thyroid gland is unique among endocrine glands in storing its principle hormonal product-the two very small thyroid hormones (TH)-as components of a 1000-fold larger precursor-thyroglobulin (Tg)-that is secreted and stored in the colloid, outside of the thyroid cell (1, 2).