MICROANATOMY

Detailed explanation-1: -Regulation of thyroid hormone starts at the hypothalamus. The hypothalamus releases thyrotropin-releasing hormone (TRH) into the hypothalamic-hypophyseal portal system to the anterior pituitary gland. TRH stimulates thyrotropin cells in the anterior pituitary to the release of thyroid-stimulating hormone (TSH).

Detailed explanation-2: -The thyroid gland is regulated by a negative feedback loop. The loop includes the hypothalamus and pituitary gland in addition to the thyroid. Here’s how thyroid regulation works. The hypothalamus secretes thyrotropin-releasing hormone, or TRH.

Detailed explanation-3: -Regulation and release of the thyroid hormones occurs as a negative feedback loop. What does this mean? In simple terms, a negative feedback loop means that as something increases, the production of whatever is causing the increase slows down.

Detailed explanation-4: -Negative Feedback Mechanism The hormone secreted by the hypothalamus stimulates the pituitary gland to release thyroid stimulating hormone. In turn, the thyroid stimulating hormone triggers the thyroid gland to release its hormones.