MICROANATOMY

Detailed explanation-1: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.

Detailed explanation-2: -Connective tissue consists of cells, fibers, and ground substance. The ground substance consisting of glycoproteins and water, and the insoluble protein fibers collectively are called matrix. Connective tissue can be classified as loose or dense.

Detailed explanation-3: -[5] Mesenchyme differentiates into chondroblasts, which are the cells that secrete the major components of the extracellular matrix-the most important of these components for cartilage formation being aggrecan and type II collagen.