MICROANATOMY

Detailed explanation-1: -At the end of a bone formation cycle, a subpopulation of osteoblasts becomes osteocytes incorporated into the bone matrix. This process is accompanied by conspicuous morphological and ultrastructural changes, including the reduction of the round osteoblast size.

Detailed explanation-2: -The osteoblasts are the cells responsible for the synthesis of the bone matrix, comprising both collagen fibres and ground substance.

Detailed explanation-3: -Osteocytes regulate local mineral deposition and chemistry at the bone matrix level, and they also function as endocrine cells producing factors that target distant organs such as the kidney to regulate phosphate transport. Osteocytes appear to be the major local orchestrator of many of bone’s functions.

Detailed explanation-4: -Osteocytes are the most abundant type of cell in mature bone tissue. They also are long-lived, surviving as long as the bone they occupy exists. The osteocyte is capable of bone deposition and resorption.