MICROANATOMY

EPITHELIUM CONNECTIVE TISSUE SKIN

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The major constituent of connective tissue is the extracellular matrix (ECM). ECM is comprised of
A
Protein fibres
B
Ground substance
C
Epithelial cells
D
Fibroblasts
Explanation: 

Detailed explanation-1: -Each type of connective tissue in animals has a type of ECM: collagen fibers and bone mineral comprise the ECM of bone tissue; reticular fibers and ground substance comprise the ECM of loose connective tissue; and blood plasma is the ECM of blood.

Detailed explanation-2: -Major components include collagens, proteoglycans, elastin, and cell-binding glycoproteins, each with distinct physical and biochemical properties. Collagen is composed of 3 polypeptide chains that form a triple helical structure.

Detailed explanation-3: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.

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