EPITHELIUM CONNECTIVE TISSUE SKIN
CONNECTIVE TISSUE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Fibroblast
|
|
|
Mast cell
|
|
|
Macrophages
|
|
|
None of the above
|
Detailed explanation-1: -Basophils. Basophils and mast cells share functional similarities and are involved in immediate hypersensitivity reactions, as well as in longterm inflammatory or immunologic responses. Basophils secrete cytokines such as IL-4 and histamine, which can play a role in the ongoing allergic response.
Detailed explanation-2: -The IgE-primed mast cell releases granules and powerful chemical mediators, such as histamine, cytokines, granulocyte macrophage colony-stimulating factor (GM-CSF), leukotrienes, heparin, and many proteases into the environment. These chemical mediators cause the characteristic symptoms of allergy.
Detailed explanation-3: -Mast Cells and Immunoglobulin E Degranulation results in the release of inflammatory mediators (e.g., histamine, prostaglandins, leukotrienes, kinins, serotonin, heparin, and serine proteases).