MICROANATOMY

EPITHELIUM CONNECTIVE TISSUE SKIN

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are the two main structures of the extracellular matrix
A
Ground substance and fibers
B
Ground substance and fluid
C
Fluid and fibers
D
None of the above
Explanation: 

Detailed explanation-1: -The extracellular matrix of both loose and dense connective tissue proper is composed of amorphous ground substance, extracellular fluid, and collagen and elastic fibers.

Detailed explanation-2: -Fibroblasts (which secrete the fibers and ground substance of the extracellular matrix).

Detailed explanation-3: -Collagens, which constitute the main structural element of the ECM, provide tensile strength, regulate cell adhesion, support chemotaxis and migration, and direct tissue development (Rozario and DeSimone, 2010).

Detailed explanation-4: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.

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