MICROANATOMY

Detailed explanation-1: -The extracellular matrix of both loose and dense connective tissue proper is composed of amorphous ground substance, extracellular fluid, and collagen and elastic fibers.

Detailed explanation-2: -[1] The composition of the dermis is mainly fibrous, consisting of both collagen and elastic fibers. Between the fibrous components lies an amorphous extracellular “ground substance” containing glycosaminoglycans, such as hyaluronic acid, proteoglycans, and glycoproteins.

Detailed explanation-3: -There are two main types of fibre; collagen, and elastin and fibronectin. You may also come across Fibronectin which is a non-collagenous fibrous connective protein that helps cells to stick to the extracellular matrix.

Detailed explanation-4: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.