MICROANATOMY

Detailed explanation-1: -Mast cells are multifunctional bone marrow-derived tissue-dwelling cells that are the major producer of histamine in the body.

Detailed explanation-2: -Mast cells are allergy cells responsible for immediate allergic reactions. They cause allergic symptoms by releasing products called “mediators” stored inside them or made by them.

Detailed explanation-3: -Abstract. Mast cells play a critical role in the pathogenesis of allergic asthma. Histamine is a central mediator released from mast cells through allergic reactions. Histamine plays a role in airway obstruction via smooth muscle contraction, bronchial secretion, and airway mucosal edema.