MICROANATOMY

Detailed explanation-1: -Keratin intermediate filaments are abundant in epithelia and form cytoskeletal networks that contribute to cell type–specific functions, such as adhesion, migration, and metabolism. A perpetual keratin filament turnover cycle supports these functions.

Detailed explanation-2: -In such tissues, one of the primary roles of keratin filaments is to resist chemical stresses and assist the cell in maintaining a polarized cytoarchitecture (Omary et al. 2009). As discussed below, plakin proteins mediate physical attachments among keratin IFs and other elements within the cell.

Detailed explanation-3: -Intermediate filaments (IFs) together with actin filaments and microtubules are major components of the cytoskeleton. The cytoplasmic IF cytoskeleton of mammalian epithelial cells consists of equal amounts of type I and type II keratin polypeptides. More items •27-Jun-2016