MICROANATOMY

Detailed explanation-1: -Most cell types are polarized with distinct structural orientations or protein localization patterns that allow cells to perform specialized functions. Epithelial cell polarity is characterized by cells with apical and basolateral membrane domains separated by adherens and tight junctions.

Detailed explanation-2: -Epithelial cells have a free surface called the apical surface. We often think of this part of the epithelial cell as the top of the cell, however, the free surface can face any direction so long as it is facing the external environment, such as the opening of a cavity or the surface of the skin.