MICROANATOMY

Detailed explanation-1: -The role of the proliferative capacity of the basal layer is therefore to maintain the integrity of the epithelium by increasing or decreasing the mitotic rate. The feedback in the basal layer required to achieve this has not been elucidated.

Detailed explanation-2: -Basal stem cells fuel development, homeostasis, and regeneration of the epidermis. The proliferation and fate decisions of these cells are highly regulated by their microenvironment, including the basement membrane and underlying mesenchymal cells.

Detailed explanation-3: -Results: The basal cell layer represents the proliferative compartment and most probably houses the prostatic stem cell population. Basal cells are targets of several regulatory factors including estrogens, androgens, epidermal growth factor and other nonsteroidal growth factors.