MICROANATOMY

Detailed explanation-1: -Collagen fibers form the extracellular framework of all tissues and are essential for tensile strength. The collagen molecules in these fibers are synthesized as larger precursor proteins, known as procollagens, from which large propeptide domains are enzymatically cleaved en bloc.

Detailed explanation-2: -The reticular fibers consist of collagen fibrils about 20-40 nm in diameter, which run singly or in small bundles. They are usually interwoven elaborately to form thin lace-like sheets or sheaths attaching to basal laminae of such cells as epithelial, endothelial and muscular cells.

Detailed explanation-3: -It consists of collagen fibrils composed of a staggered array of ultra-long tropocollagen (TC) molecules. Theoretical and molecular modeling suggests that this natural design of collagen fibrils maximizes the strength and provides large energy dissipation during deformation, thus creating a tough and robust material.