MICROANATOMY

Detailed explanation-1: -Dermis: the inner layer of skin beneath the epidermis, composed of connective tissue, blood and sweat glands. It contains the nerves that process touch and pain information.

Detailed explanation-2: -These simple receptors are found in the dermis around the base of hair follicles and close to the surface of the skin (epidermis) where the hair emerges from the skin. These free endings respond to changes in temperature (warmth and cold) and other events associated with tissue damage.

Detailed explanation-3: -The pain receptors are nociceptors. They are known to exist in muscle, joints, and skin. Each nociceptor has selective sensitivity to mechanical (muscle-fiber stretching), chemical (including lactic acid), and thermal stimuli.