MICROANATOMY

Detailed explanation-1: -Contact dermatitis is an itchy rash caused by direct contact with a substance or an allergic reaction to it. The rash isn’t contagious, but it can be very uncomfortable. Many substances can cause this reaction, such as cosmetics, fragrances, jewelry and plants. The rash often shows up within days of exposure.

Detailed explanation-2: -Very irritating chemicals may cause a reaction after just a short period of contact. Milder chemicals can also cause a reaction after repeated contact. People who have atopic dermatitis are at increased risk of developing irritant contact dermatitis.

Detailed explanation-3: -Contact dermatitis (CD) is an inflammatory skin disease caused by chemicals or metal ions that exert irritant (toxic) effects, or by small reactive chemicals (contact allergens) that modify proteins and induce immune responses (predominantly by T-cell response) (1).

Detailed explanation-4: -There are two main types of contact dermatitis: irritant and allergic.