MICROANATOMY

EPITHELIUM CONNECTIVE TISSUE SKIN

INTEGUMENT

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Skin color is determined by (select all that apply):
A
number of melanocytes
B
melanocytes extensions
C
genetics
D
melanin color
Explanation: 

Detailed explanation-1: -Skin color is largely determined by the amount of melanin. Dark-skinned individuals produce more melanin than light-skinned individuals. At least three genes regulate the amount of melanin produced. Each gene has two forms: dark skin allele (A, B, and C) and light skin allele (a, b, and c).

Detailed explanation-2: -The production of light skin appears to be influenced by a variety of genes: DRD2, EGFR, DCT, and KITLG in Asians; KITLG, SLC24A5, TYRP1, DTNBP1, and MYO5A in Europeans; and SLC24A5 which is responsible for 25–38% of the variation in skin color between Africans and Europeans [53, 54].

Detailed explanation-3: -Human skin color is a “polygenic” trait, meaning multiple gene loci are involved in its expression. At last count, the International Federation of Pigment Cell Society has determined that there are a total of 378 genetic loci involved in determining skin color in human and mice.

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