MICROANATOMY

Detailed explanation-1: -Sweat evaporation from the skin surface plays a critical role in human thermoregulation and this is most apparent when the ability to sweat is compromised during periods of strenuous physical labor and/or exposure to hot environments [1].

Detailed explanation-2: -The primary function of sweat glands is to keep the core body temperature at approximately 37 °C by releasing sweat in a hot environment or during physical activity [189, 195]. Sweat glands are innervated by neurons, so the process of sweating is controlled by the central nervous system.

Detailed explanation-3: -Secretion. The secretion of sweat follows a Na-K-2Cl cotransport model: Release of intracellular Ca stores and an influx of extracellular Ca into the cytoplasm is triggered by binding of acetylcholine to muscarinic receptors on the basolateral membrane of the clear cell.

Detailed explanation-4: -Sweat glands are appendages of the integument.