MICROANATOMY

EPITHELIUM CONNECTIVE TISSUE SKIN

INTEGUMENT

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The more superficial cells of the epidermis become less viable and ultimately die. What two factors account for this natural demise of the epidermal cells?
A
cells are farther from the dermal blood supply
B
cells become filled with keratin
C
the cell membrane is broken down
D
cells are destroyed by Langerhans cells
Explanation: 

Detailed explanation-1: -The primary factor in the demise of the cells of the outer epidermal layer, known as the cornified layer, is the loss of water in the cells in the layer of dying cells. The second factor is the infusion of keratin, a dense protein that hardens the skin cells to aid in producing a barrier against the outside world.

Detailed explanation-2: -This death occurs largely as a result of the distance the keratinocytes find themselves from the rich blood supply the cells of the stratum basale lie on top off. Devoid of nutrients and oxygen, the keratinocytes die as they are pushed towards the surface of our skin.

Detailed explanation-3: -Remember that there are no blood vessels in the epidermis so the cells get their nutrients by diffusion from the connective tissue below, therefore the cells of this outermost layer are dead.

Detailed explanation-4: -The uppermost layer of the epidermis everywhere on the body is the stratum corneum . This layer is made of flat, hard, tightly packed dead keratinocytes that form a waterproof keratin barrier to protect the underlying layers of the epidermis. Dead cells from this layer are constantly shed from the surface of the body.

There is 1 question to complete.