MICROANATOMY

Detailed explanation-1: -Thermal sweating is mediated predominately by sympathetic cholinergic stimulation. Sweat production is stimulated through the release of acetylcholine from nonmyelinated class C sympathetic postganglionic fibers, which binds to muscarinic (subtype 3) receptors on the sweat gland (see Figure 2(c)) [9].

Detailed explanation-2: -The eccrine gland is the primary gland responsible for thermoregulatory sweating in humans (110) and thus will be the focus of this review. For a review of the apocrine gland the reader is referred to other articles (28, 103). Eccrine sweat glands are distributed over nearly the entire body surface.

Detailed explanation-3: -sweat gland, either of two types of secretory skin glands occurring only in mammals. The eccrine sweat gland, which is controlled by the sympathetic nervous system, regulates body temperature. When internal temperature rises, the eccrine glands secrete water to the skin surface, where heat is removed by evaporation.