MICROANATOMY

Detailed explanation-1: -In most cases, Merkel cells complex with somatosensory afferents to form slowly adapting touch receptors; it is unclear, however, whether mechanosensory transduction occurs in the Merkel cell, the somatosensory afferent or both.

Detailed explanation-2: -Merkel cells are touch-sensitive cells that transduce touch via Piezo2 channels. The Merkel cell-neurite complex contains two sensory receptor cell types. Merkel cells and neurons together mediate different aspects of touch responses.

Detailed explanation-3: -A special type of cell found right below the epidermis (top layer of skin). These cells are very close to the nerve endings that receive the sensation of touch and may be involved in touch. The cells also contain substances that may act as hormones.

Detailed explanation-4: -Our sense of touch, or tactile sensation, is mediated by cutaneous mechanoreceptors located in our skin. There are four main types of cutaneous mechanoreceptors: Pacinian corpuscles, Meissner’s corpuscles, Merkel’s discs, and Ruffini endings.