MICROANATOMY

Detailed explanation-1: -"Xanthoderma” is a term that describes a yellow to orange macular discoloration of the skin. The cause of this finding ranges from benign to potentially life-threatening disease. To date the literature fails to comprehensively review the various causes and workup of this clinical manifestation.

Detailed explanation-2: -The primary factor differentiating carotenoderma from jaundice is the characteristic sparing of the sclerae in carotenoderma, which would be involved in jaundice if the bilirubin is at a level to cause skin findings. In contrast to jaundice, carotenoderma is reported to be better observed under artificial light.

Detailed explanation-3: -What causes carotenoderma? Carotenoderma is due to carotenaemia. Primary carotenaemia is usually due to excessive intake of carotenoid-containing foods or supplements. Carotene is found in all pigmented fruits and vegetables.