MICROANATOMY

Detailed explanation-1: -Merkel cells are in the layer of basal cells at the deepest part of the epidermis and are connected to nerves.

Detailed explanation-2: -Highlights. Merkel cells are touch-sensitive cells that transduce touch via Piezo2 channels. The Merkel cell-neurite complex contains two sensory receptor cell types.

Detailed explanation-3: -Merkel cells are found in the epidermis. Merkel cells normally exist in the bottom (basal) layer of the epidermis, about 0.1 mm from skin’s surface. (outer layer of the skin). They were originally described in the late 1800s by Friedrich Merkel, a German anatomist.

Detailed explanation-4: -Merkel cells are epithelial neuroendocrine cells. Although their origin is unclear, they are thought to arise from epidermal ectoderm rather than neural crest. Merkel cells are rare and are found in the basal layer of the epidermis and around the bulge region of hair follicles.

Detailed explanation-5: -Merkel nerve endings are mechanoreceptors, a type of sensory receptor, that are found in the basal epidermis and hair follicles. They are nerve endings and provide information on mechanical pressure, position, and deep static touch features, such as shapes and edges.