INTRODUCTION TO MICROSCOPY CELL BIOLOGY
CELL JUNCTIONS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Claudins and occludins form an impermeable seal all the way around the apical portion of an epithelial cell. This describes
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Tight junction
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Gap Junction
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Belt Desmosomes
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All of the above
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Explanation:
Detailed explanation-1: -Claudins and occludins associate with intracellular peripheral membrane proteins called ZO proteins (a tight junction is also known as a zonula occludens), which anchor the strands to the actin cytoskeleton.
Detailed explanation-2: -The three major transmembrane proteins are occludin, claudins, and junction adhesion molecule (JAM) proteins. These associate with different peripheral membrane proteins such as ZO-1 located on the intracellular side of plasma membrane, which anchor the strands to the actin component of the cytoskeleton.
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