MICROANATOMY

INTRODUCTION TO MICROSCOPY CELL BIOLOGY

CELL JUNCTIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Claudins and occludins form an impermeable seal all the way around the apical portion of an epithelial cell. This describes
A
Tight junction
B
Gap Junction
C
Belt Desmosomes
D
All of the above
Explanation: 

Detailed explanation-1: -Claudins and occludins associate with intracellular peripheral membrane proteins called ZO proteins (a tight junction is also known as a zonula occludens), which anchor the strands to the actin cytoskeleton.

Detailed explanation-2: -The three major transmembrane proteins are occludin, claudins, and junction adhesion molecule (JAM) proteins. These associate with different peripheral membrane proteins such as ZO-1 located on the intracellular side of plasma membrane, which anchor the strands to the actin component of the cytoskeleton.

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