MICROANATOMY

Detailed explanation-1: -Anchoring-type junctions not only hold cells together but provide tissues with structural cohesion.

Detailed explanation-2: -Septate junctions serve as occluding junctions in invertebrate tissues. The main types of anchoring junctions in vertebrate tissues are adherens junctions, desmosomes, focal adhesions, and hemidesmosomes.

Detailed explanation-3: -Vertebrate tissues contain two principal types of adhesive intercellular junctions: adherens junctions (AJs) and desmosomes. AJs are involved in dynamic cell interactions in development and disease, whereas desmosomes are responsible for strong adhesion in epithelia and cardiac muscle (1, 2).

Detailed explanation-4: -Desmosomes connect two cells together. A desmosome is also known as a spot desmosome or macula adherens (macula = latin for spot), because it is circular or spot like in outline, and not belt-or band shaped like adherens junctions.