MICROANATOMY

Detailed explanation-1: -Occluding junctions seal cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.

Detailed explanation-2: -Depending upon the organ function, tight junctions can be tight or leaky. The leaky tight junctions permit the movement of a large amount of material across them and are thus referred to posses low Trans-Epithelial resistance (TER). A perfect example of this is the human gastrointestinal tract (GIT).

Detailed explanation-3: -Tight junctions form a water tight seal and prevent material from passing between cells. Desmosomes form links between cells, and provide a connection between intermediate filaments of the cell cytoskeletons of adjacent cells. This structure gives strength to tissues.