MICROANATOMY

Detailed explanation-1: -Hemoglobins are produced only in erythroid cells, where they are the major protein. The multi-subunit hemoglobin binds oxygen cooperatively in the lungs, transports the oxygen through the blood, and releases it in peripheral tissues to support oxidative metabolism.

Detailed explanation-2: -The HBB gene provides instructions for making a protein called beta-globin. Beta-globin is a component (subunit) of a larger protein called hemoglobin, which is located inside red blood cells.

Detailed explanation-3: -Hemoglobin is the protein inside red blood cells. It carries oxygen. Red blood cells also remove carbon dioxide from your body, bringing it to the lungs for you to exhale.

Detailed explanation-4: -Adult hemoglobin is composed of two alpha () and two beta () polypeptide chains. There are two copies of the hemoglobin alpha gene (HBA1 and HBA2), which each encode an -chain, and both genes are located on chromosome 16.