MICROANATOMY

Detailed explanation-1: -The process of turning genes on and off is known as gene regulation. Gene regulation is an important part of normal development. Genes are turned on and off in different patterns during development to make a brain cell look and act different from a liver cell or a muscle cell, for example.

Detailed explanation-2: -During the differentiation of pluripotent cells such as embryonic stem (ES) cells, pluripotency-associated genes are repressed, potentially permanently, as a result of DNA methylation. At the same time, developmental genes begin to be expressed, and there is an increase in H3K4 methylation.

Detailed explanation-3: -During cell differentiation, unspecialized cells mature into and evolve to perform a specific function. This also occurs due to differential gene expression, changes in their shape, cell wall, protoplasm, etc.