MICROANATOMY

INTRODUCTION TO MICROSCOPY CELL BIOLOGY

DIFFERENTIATED CELL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
To treat Stargardt’s disease, stem cells are used to replace
A
neurons
B
epithelial cells in retina
C
insulin-producing cells
D
red bone marrow cells
Explanation: 

Detailed explanation-1: -Theoretically, this therapy will enable the generation of new retinal cells from stem cells to replace the damaged cells in the diseased retina. In addition, stem cells are able to perform multiple functions, such as immunoregulation, anti-apoptosis of neurons, and neurotrophin secretion.

Detailed explanation-2: -The treatment, a small drop of liquid delivered by an intravitreal injection, uses a human-engineered virus to deliver copies of the Multi-Characteristic Opsin (MCO) gene to bipolar cells-cells that don’t normally sense light but often survive after photoreceptors are lost to advanced retinal disease.

Detailed explanation-3: -Stem cell treatments appear to offer hope to people with few options to recover vision. This includes people with forms of age-related macular degeneration (AMD), retinitis pigmentosa (RP), and Stargardt disease. Some clinics across the United States offer “stem-cell therapy” to people outside of clinical trials.

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