INTRODUCTION TO MICROSCOPY CELL BIOLOGY
DIFFERENTIATED CELL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Induced purpose stem cells, mean embryo cells were made into adult-like cells
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Induced purpose stem cells, mean adult cells were reversed to baby cells
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Induced pluripotent stem cells, mean adult cells were made into embryo-like cells
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Induced pluripotent stem cells, mean cells were totipotent and are now pluripotent
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Detailed explanation-1: -Induced pluripotent stem (iPS) cells, are a type of pluripotent stem cell derived from adult somatic cells that have been genetically reprogrammed to an embryonic stem (ES) cell-like state through the forced expression of genes and factors important for maintaining the defining properties of ES cells.
Detailed explanation-2: -Most induced pluripotent stem (iPS) cells are generated by retroviral or lentiviral transduction of reprogramming factors. Multiple viral integrations into the genome may cause insertional mutagenesis and may increase the risk of tumour formation.
Detailed explanation-3: -Induced pluripotent stem cells are widely used in therapeutics for disease modeling, regenerative medicine, and drug discovery (Figure 4). There are many applications of iPSCs in the fields of gene therapy, disease modeling and drug discovery.
Detailed explanation-4: -An attractive feature of human iPS cells is the ability to derive them from adult patients to study the cellular basis of human disease. Since iPS cells are self-renewing and pluripotent, they represent a theoretically unlimited source of patient-derived cells which can be turned into any type of cell in the body.